Chromatography is the separation of a mixture of compounds into its individual components based on their relative interactions with an inert matrix. Low Pressure Chromatography has column packed at lower pressure. The packing pressure depend on the operating pressure range of the resin, used for packing. Ion Exchange resin is one of the example of Low Pressure Chromatography. Ion exchange chromatography or ion chromatography is a process that allows the separation of ions and polar molecules based on their affinity to ion exchangers. The principle of separation is thus by reversible exchange of ions between the target ions present in the sample solution to the ions present on ion exchangers. In this process two types of exchangers i.e., cationic and anionic exchangers can be used. Cationic exchangers possess negatively charged group, and these will  attract positively charged cations.  These exchangers are also  called  " Acidic